What is the side effect of streptomycin injection?

Nausea, vomiting, stomach upset, or loss of appetite may occur. Pain/irritation/redness may occur at the injection site. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Why streptomycin is no longer used?

Even in the treatment of septicemia, urinary tract and gastrointestinal tract infections, and numerous other infections due to Gram-positive and Gram-negative organisms, streptomycin was replaced by other aminoglycosides with less intense ototoxicity and renal toxic effects and propensities for resistance.

Is Serious side effects of streptomycin?

Tell your doctor if you have serious side effects of Streptomycin including:

• muscle weakness,
• persistent diarrhea even after stopping this medication,
• easy bleeding or bruising,
• fast heartbeat,
• new signs of infections (e.g., high fever, persistent cough),
• changes in the amount of urine, or.
• unusual tiredness.

How do you give a streptomycin injection?

Give by IM inj into mid-lateral thigh. Alternate injection sites. 20–40mg/kg (max 1g) once daily, or 25–30mg/kg (max 1.5g) two or three times weekly. Max 120g over entire course of therapy.

How long does streptomycin last in the body?

Streptomycin is excreted by glomerular filtration. In patients with normal kidney function, between 29\% and 89\% of a single 600 mg dose is excreted in the urine within 24 hours. Any reduction of glomerular function results in decreased excretion of the drug and concurrent rise in serum and tissue levels.

Can streptomycin cause hearing loss?

Streptomycin may cause nerve damage or hearing loss, especially if you have kidney disease or use certain other medicines. Tell your doctor right away if you have severe dizziness, hearing problems, vision problems, balance problems, trouble concentrating, muscle weakness, numbness, or tingling.

Is streptomycin still used today?

Streptomycin was discovered in 1943. It was the first antibiotic discovered that was effective against TB. Today it is widely used as a first line TB medicine in patients that have previously been treated for TB.

Can streptomycin cause blindness?

A case of transient blindness occurring during long-term therapy with streptomycin and chloramphenicol is described. The literature is reviewed. It is not possible to decide whether streptomycin or chloramphenicol acting alone or in conjunction was responsible for this unfortunate complication.

Can streptomycin cure gonorrhea?

Streptomycin is so ineffective now against gonorrhea that it is no longer acceptable even as a first treatment in patients who are allergic to penicillin. In London, the failure rate with streptomycin is 31.7\%.

Can streptomycin cure typhoid?

NEW DRUG IS USED TO TREAT TYPHOID; Streptomycin Found Effective Against Disease for Which No Cure Was Known 3 DOCTORS REPORT FIND Of 5 Persons Treated During Experiments, 3 Were Cured by Philadelphia Physicians.

Can streptomycin cause deafness to unborn baby?

The risk of deafness developing in the unborn child following the use of streptomycin (SM) during pregnancy remains uncertain. We have followed up 30 children whose mothers received SM during pregnancy.