What is the most common site for sepsis?

The most common site of infection was the lungs (31.0\%), followed by the intra-abdomen (26.3\%), the urinary tract (18.4\%), and soft tissue (10.9\%). The characteristics of the patients with severe sepsis were heterogeneous across all seven infection sites.

What part of the body is affected by sepsis?

In sepsis, blood pressure drops, resulting in shock. Major organs and body systems, including the kidneys, liver, lungs, and central nervous system may stop working properly because of poor blood flow. A change in mental status and very fast breathing may be the earliest signs of sepsis.

Which organs are affected first by sepsis?

As severe sepsis usually involves infection of the bloodstream, the heart is one of the first affected organs.

What are the most common causes of sepsis?

Bacterial infections are the most common cause of sepsis. Sepsis can also be caused by fungal, parasitic, or viral infections. The source of the infection can be any of a number of places throughout the body.

What are the three most common causes of sepsis?

While any type of infection — bacterial, viral or fungal — can lead to sepsis, infections that more commonly result in sepsis include infections of:

• Lungs, such as pneumonia.
• Kidney, bladder and other parts of the urinary system.
• Digestive system.
• Bloodstream (bacteremia)
• Catheter sites.
• Wounds or burns.

What is the pathophysiology of sepsis?

Sepsis results when an infectious insult triggers a localized inflammatory reaction that then spills over to cause systemic symptoms of fever or hypothermia, tachycardia, tachypnea, and either leukocytosis or leukopenia. These clinical symptoms are called the systemic inflammatory response syndrome.

What is the anatomy of sepsis?

At the cellular level, sepsis is characterized by changes in the function of endothelial tissue (the endothelium forms the inner surface of blood vessels), in the coagulation (blood clotting) process, and in blood flow.