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What is the disadvantage of paper chromatography?

What is the disadvantage of paper chromatography?

Disadvantages of Paper Chromatography Separation of complex mixtures is difficult. It is not compatible with testing large amounts of samples. This technique is not suitable for the separation of volatile substances such as hydrocarbons and volatile fatty acids. Not suitable for quantitative analysis.

Which among the following is a disadvantage of chromatography?

Explanation: The disadvantage of coiled or helical shaped packed chromatographic column is that it cannot be repacked easily. It is compact in size and can easily be heated in an even manner.

What are the limitations of chromatography?

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Large quantity of sample cannot be applied on paper chromatography.

  • In quantitative analysis paper chromatography is not effective.
  • Complex mixture cannot be separated by paper chromatography.
  • Less Accurate compared to HPLC or HPTLC.
  • What are the advantages of using chromatography?

    The Advantages of Chromatography

    • Precise separation, analyses, and purification is possible using chromatography.
    • It requires very low sample volumes.
    • It works on a wide range of samples including drugs, food particles, plastics, pesticides, air and water samples, and tissue extracts.

    Which of the following is not a disadvantage of pneumatic pumps used in liquid chromatography?

    2. Which of the following is not a disadvantage of Pneumatic pumps used in liquid chromatography? Explanation: Pneumatic pumps provide pulse free output.

    What are sources of error in chromatography lab?

    On the other hand, although currently considered the method of choice for carotenoids, high performance liquid chromatography (HPLC) is subject to various sources of errors, such as: incompatibility of the injection solvent and the mobile phase, resulting in distorted or split peaks; erroneous identification; …

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    What are the differences between paper chromatography and thin layer chromatography?

    Paper chromatography requires less preparation, whereas thin layer chromatography requires more preparation time. The stationary phase of paper chromatography is the water trapped in the cellulose filter paper. The stationary phase of the thin layer chromatography is the glass plates coated with silica gel.

    What might be a disadvantage of a very long column?

    Without having to redevelop the method, the increased resolution can readily be achieved by increasing the column length. A disadvantage of using longer columns is that the analysis time has to be increased accordingly.

    Which of the following is the disadvantage of reciprocating pump used in liquid chromatography Mcq?

    Which of the following is the disadvantage of reciprocating pump used in liquid chromatography? Explanation: The disadvantage of reciprocating pump used in liquid chromatography is that it produces pulsed flow. Therefore, the flow must be damped before it affects the column.