What is calcitriol and what is its function?
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What is calcitriol and what is its function?
Calcitriol is a form of vitamin D3. Vitamin D helps your body absorb calcium from the stomach. Calcitriol is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people who have chronic kidney failure and are not receiving dialysis.
Is vitamin D and calcitriol the same thing?
Vitamin D2 or D3 must then be first hydroxylated in the liver and then in the kidneys to become active. At this point, as biologically active 1,25-OH-cholecalciferol (also called calcitriol), this form of vitamin D can exert its endocrine effects (1).
Is calcitriol the same as calcium?
Calcitriol is a synthetic version of Vitamin D3 used to treat calcium deficiency with hypoparathyroidism (decreased functioning of the parathyroid glands) and metabolic bone disease in people with chronic kidney failure. Calcitriol is available under the following different brand names: Calcijex and Rocaltrol.
What is another name for calcitriol?
calcitriol
| Synonym: | 1,25-dihydroxycholecalciferol |
|---|---|
| US brand name: | Rocaltrol |
| Abbreviation: | 1,25(OH)2-D3 CALTROL |
| Chemical structure: | (1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol |
Is calcitriol bad for kidneys?
Circulating calcitriol, a key metabolite in maintaining calcium and phosphorus homeostasis, is produced in the kidney. In kidney failure, calcitriol levels progressively decrease, contributing to the development of renal secondary hyperparathyroidism (SHPT).
What is calcitriol used for in dogs?
Calcitriol (brand names: Rocaltrol®, Calcijex®) is a form of vitamin D used to treat low blood calcium associated with low parathyroid gland function. It may also be helpful in treating chronic kidney disease, certain cancers such as mast cell tumors, and certain skin diseases.
Is vitamin D3 a hormone?
Vitamin D is a hormone produced by the kidneys that helps to control the concentration of calcium in the blood and is vital for the development of strong bones.
What’s vitamin D3 do?
Vitamin D (ergocalciferol-D2, cholecalciferol-D3, alfacalcidol) is a fat-soluble vitamin that helps your body absorb calcium and phosphorus. Having the right amount of vitamin D, calcium, and phosphorus is important for building and keeping strong bones.
What can replace calcitriol?
We conclude that treatment with twice daily sc PTH provides a safe and effective alternative to calcitriol therapy and is able to maintain normal serum calcium levels without hypercalciuria for at least 3 yr in patients with hypoparathyroidism.
In which food vitamin D3 is found?
Food Sources Few foods are naturally rich in vitamin D3. The best sources are the flesh of fatty fish and fish liver oils. Smaller amounts are found in egg yolks, cheese, and beef liver.
Can too much calcium hurt your kidneys?
Hypercalcemia is a condition in which the calcium level in your blood is above normal. Too much calcium in your blood can weaken your bones, create kidney stones, and interfere with how your heart and brain work.
Is vitamin d3 hard on your kidneys?
Vitamin D has been reported to have a wide range of benefits. However, a recent case study indicates that excessive use of vitamin D can cause kidney damage in people who are not deficient in the vitamin.