What drug class is aprepitant?

Aprepitant is in a class of medications called antiemetics. It works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.

What is another name for aprepitant?

Aprepitant, sold under the brand name Emend among others, is a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. It may be used together with ondansetron and dexamethasone. It is taken by mouth.

Can aprepitant be used long term?

Take this medicine only as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This medicine comes with patient information leaflet. Read and follow these instructions carefully.

What drug class is Emend?

Emend is a prescription medicine used to treat the symptoms of Chemotherapy-Induced Nausea and Vomiting. Emend may be used alone or with other medications. Emend belongs to a class of drugs called Antiemetic Agents; NK1 Receptor Antagonists.

How is aprepitant given?

Aprepitant injection comes as an emulsion (liquid) and fosaprepitant injection comes as a powder to be mixed with liquid and given intravenously (into a vein) by a doctor or nurse in a medical facility.

How long does aprepitant take to work?

The first dose of aprepitant is usually given 30 to 60 minutes before treatment with chemotherapy.

How does an aprepitant work?

Aprepitant is used with other medications to help prevent nausea and vomiting caused by cancer drug treatment (chemotherapy). Aprepitant works by blocking one of the body’s natural substances (substance P/neurokinin 1) that causes vomiting. This medication will not treat nausea or vomiting that has already started.

How does aprepitant affect birth control?

Aprepitant can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using aprepitant, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.

Is aprepitant the same as Emend?

Aprepitant (Emend) is an antiemetic. It blocks a chemical in the brain called substance P, which controls your vomiting reflex.

Can you take Emend every day?

Emend is not for long-term use. You will most likely need only 1 to 3 doses. The first dose is usually given 30 to 60 minutes before treatment with chemotherapy. Follow your doctor’s dosing instructions very carefully.

How is aprepitant administered?

Chemotherapy-Induced Nausea and Vomiting (CINV) [9] Aprepitant is available for oral suspension prepared by mixing the contents of one pouch of powder with 4.6 ml of water. The resulting suspension yields a 25 mg/ml strength for oral administration to pediatric patients or adults who cannot swallow capsules.

Does aprepitant make you drowsy?

SIDE EFFECTS: Tiredness and hiccups may occur. If either of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.