What are Isosteres with example?

Isosteres are atoms, molecules, or ions of similar size containing the same number of atoms and valence electrons. Example 1. Consider neon, the noble gas at the end of the second row of the periodic table.

What does Isosteres mean?

Hans Erlenmeyer extended the concept to biological systems in 1932. Classical isosteres are defined as being atoms, ions and molecules that had identical outer shells of electrons, This definition has now been broadened to include groups that produce compounds that can sometimes have similar biological activities.

Which pairs are Isosteres?

Detailed Solution. Isosters are molecules or ions that have a similar shape and often have similar electronic properties. CO2 and N2O can form set of isosters.

What are Isosteres in medicinal chemistry?

In medicinal chemistry, bioisosteres are chemical substituents or groups with similar physical or chemical properties which produce broadly similar biological properties to another chemical compound.

What is Isosteres 11?

We can define isostere as the molecules or ions that have a similar shape and often have similar electronic properties.

How many types of classical Isosteres are there?

Classical bioisosteres can be further subdivided into five classes: 1) monovalent atoms or groups (D and H; F and H; C and Si; Cl, Br, SH, and OH; NH and OH; RSH and ROH, –Cl, –PH2, –SH), 2) divalent atoms or groups (–CH2, –NH, –O, –S, –Se–, -COCH2-), 3) trivalent atoms or groups (–CH=, –N=, -P=, -As=), 4) tetravalent …

Are N2 and CO Isosteres?

CO and N2 molecules have same number of atoms as well as same number of electrons.

Are no2 and o3 Isosteres?

Explanation: NO₂⁻ and O₃ are isosteres because both specifies have same (=3) and number of electrons (24).

Which of these are Isosters?

Answer: option (a) CO2 and N2O is pair of isosters.

What is the difference between Isoelectronic and Isosteres?

The key difference between isoelectronic and isosteres is that isoelectronic chemical species have similar electronic configurations whereas isosteres are chemical species having similar size, the same number of atoms and valence electrons.

What are Isodiaphers and Isosteres?

Isosteres are molecules or ions that have a similar shape and often have similar electronic properties. Isodiaphers are atoms with different atomic number and mass number, but with the same difference between the number of neutrons and the number of protons.

Which species are Isosteres of each other?

What are Isosteres? The term isostere refers to chemical species having a similar size, the same number of atoms and the same number of valence electrons. The chemical species we are considering in this context are molecules or ions. For example, benzene and thiophene are isosteric molecules.