How are quaternary ammonium compounds made?
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How are quaternary ammonium compounds made?
Quaternary ammonium compounds are prepared by the alkylation of tertiary amines with a halocarbon. In older literature this is often called a Menshutkin reaction, however modern chemists usually refer to it simply as quaternization.
What are quaternary ammonium compounds?
Quats (quaternary ammonium compounds) are potent disinfectant chemicals commonly found in disinfectant wipes, sprays and other household cleaners that are designed to kill germs. It is often the stuff that allows a product to claim to be antibacterial, as they are certified by the EPA as pesticides.
Which of the following mechanisms is involved in the absorption of quaternary ammonium compounds?
Many quaternary ammonium salts are incompletely absorbed after their oral administration and may also be actively secreted into the intestine. This secretion appeared to be responsible for the low oral bioavailability of the compound, probably mediated by p-gp (p-glycoprotein) located in the apical membrane.
What is the formula for quaternary ammonium?
CID 73357425
| PubChem CID | 73357425 |
|---|---|
| Chemical Safety | Laboratory Chemical Safety Summary (LCSS) Datasheet |
| Molecular Formula | C32H70Cl2+4 |
| Synonyms | Quaternary ammonium compounds, di-C8-10-alkyldimethyl, chlorides J-524169 |
| Molecular Weight | 525.8 |
How does quaternary ammonium work?
Quaternary ammonium compounds work by denaturing the proteins of the bacterial or fungal cell, affecting the metabolic reactions of the cell and causing vital substances to leak out of the cell, causing death.
How do quaternary ammonium compounds work?
What is the mode of action for quaternary ammonium compounds?
Mode of Action: The bactericidal action of the quaternaries has been attributed to the inactivation of energy-producing enzymes, denaturation of essential cell proteins, and disruption of the cell membrane.
What is the concentration of quaternary ammonium compounds?
QACs are used at concentrations ranging from 200 to 400 ppm for various food-contact surfaces. QACs are generally very stable, mostly unaffected by pH levels, and remain effective on a food-contact surface for a long time.
Where is quaternary ammonium used?
Uses: The quaternaries commonly are used in ordinary environmental sanitation of noncritical surfaces, such as floors, furniture, and walls. EPA-registered quaternary ammonium compounds are appropriate to use for disinfecting medical equipment that contacts intact skin (e.g. blood pressure cuffs).