Questions

What is the treatment for stage 1b uterine cancer?

What is the treatment for stage 1b uterine cancer?

Surgery is the main treatment for stage 1 womb cancer. Your surgeon removes your womb and cervix. This is a hysterectomy. They usually also remove both of your fallopian tubes and ovaries.

Can Stage 1b endometrial cancer be cured?

Stage IB is cancer that invades less than one half of the muscle wall of the uterus. Stage IC is cancer that invades more than one half of the muscle wall of the uterus. Stage I uterine cancer is curable with surgery alone for the majority of patients.

What is endometrioid adenocarcinoma grade 2?

International Federation of Gynecology and Obstetrics (FIGO) Grade 2 endometrial endometrioid adenocarcinoma carries a 88\% 5-yr survival rate. They are defined by >5\% but <50\% solid epithelial component. A small subset may display <5\% solid growth, but marked nuclear atypia and are designated Grade 2.

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Is Stage 2 endometrial cancer curable?

Stage IIB cancer involves the uterus and extends into deep layers of the cervix. Stage I and II uterine cancers are curable with surgery alone for the majority of patients. Optimal treatment may require additional therapeutic approaches in selected situations.

Can Stage 1 uterine cancer come back?

Recurrent uterine cancer Uterine cancer may come back in the uterus, pelvis, lymph nodes of the abdomen, or another part of the body. If there is a recurrence, this tends to occur within 3 years of the original diagnosis, but later recurrences can sometimes occur as well.

Does stage 1 endometrial cancer require radiation?

Stage I endometrioid cancers For women with higher grade tumors, radiation will likely be recommended after surgery. Vaginal brachytherapy (VB), pelvic radiation, or both can be used. Some younger women with early endometrial cancer may have their uterus removed without removing the ovaries.

What does Figo Grade 1 mean?

The grading system currently used for endometrioid adenocarcinomas is the one proposed by International Federation of Gynecology and Obstetrics (FIGO). If the tumor contains no more than 5\% of solid, non-morular component, it is Grade 1.

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What does the endometrium do?

The endometrium is the inner lining of the uterus. Each month, the endometrium thickens and renews itself, preparing for pregnancy. If pregnancy doesn’t occur, the endometrium sheds in a process known as menstruation. If conception takes place, the embryo implants into the endometrium.

Does stage 1 endometrial cancer require chemo?

Chemo is not used to treat stage I and II endometrial cancers. In most cases, a combination of chemo drugs is used. Combination chemotherapy tends to work better than one drug alone. Chemo is often given in cycles: a period of treatment, followed by a rest period.

What stage is well differentiated adenocarcinoma?

Low grade or grade I tumors are well-differentiated. This means that the tumor cells are organized and look more like normal tissue. High grade or grade III tumor cells are poorly differentiated.

Is FIGO grade the same as stage?

The 2 systems used for staging endometrial cancer, the FIGO (International Federation of Gynecology and Obstetrics) system and the American Joint Committee on Cancer TNM staging system are basically the same.

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Is adjuvant therapy effective in Stage 1 endometrial cancer?

Background: Most patients with endometrial cancer have stage I disease. Adjuvant therapy in stage IB (formerly IC) endometrial cancer is controversial, treatment options including observation or brachytherapy/ radiotherapy in grade 1-3 patients with or without chemotherapy.

Can endometrial adenocarcinoma Grade 2 be cured with surgery alone?

Conclusion: According to our experience and previously published data, most patients with FIGO Stage IB, Grade 2 endometrial carcinoma may be cured with surgery alone. Keywords: Adjuvant brachytherapy, endometrial adenocarcinoma, endometrium, radiotherapy INTRODUCTION

What are the treatment options for Stage 2 endometrial cancer?

Patients with Stage IB Grade 2 endometrial cancer are considered to have low-risk disease. Although some investigators recommend no postoperative treatment, others favor adjuvant radiotherapy, either PRT or IVRT.

How is Grade 2 endometrial carcinoma (IB) treated?

Patients and Methods: Forty-six patients with Stage IB, Grade 2 endometrial carcinoma, were treated with simple hysterectomy and bilateral oophorectomy in our institution. The mean age was 63 (range, 42-81). Surgical staging, defined as peritoneal washing and pelvic lymph node sampling was performed in 73\% of patients.