What is a CPVT test?

CPVTNext is a multi-gene panel for patients with catecholaminergic polymorphic ventricular tachycardia (CPVT). It includes RYR2, in which mutations have been identified in over 50\% of cases. Often, CPVT is asymptomatic and sudden death is the first symptom.

What are the symptoms of CPVT?

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder that causes an abnormally fast and irregular heart rhythm in response to physical activity or emotional stress. Signs and symptoms include light-headedness, dizziness, and fainting.

Is CPVT common?

The prevalence of CPVT is estimated to be about 1 in 10,000 people. However, the true prevalence of this condition is unknown.

Can CPVT be cured?

CPVT is a treatable disorder and, with correct diagnosis and treatments, most deaths are preventable.

Is CPVT hereditary?

Scientists have found three gene problems that cause CPVT. Most people get CPVT due to a faulty gene they inherit from their parents. The most common form of CPVT is a “dominant” genetic condition, which means that if one parent has the condition, each child has a 50-50 chance of getting it.

Is CPVT curable?

CPVT is a treatable disorder and, with correct diagnosis and treatments, most deaths are preventable. Physicians need to know: When to consider CPVT as a possible diagnosis. When to refer patients for diagnosis & treatment.

What is the prognosis of ventricular tachycardia?

Ventricular tachycardia may last for only a few seconds, or it can last for much longer. You may feel dizzy or short of breath, or have chest pain. Sometimes, ventricular tachycardia can cause your heart to stop (sudden cardiac arrest), which is a life-threatening medical emergency.

Can I exercise with CPVT?

Exercise is discouraged for patients who suffer from CPVT or carry one of the causative gene mutations. Abstaining from physical activity in young individuals may lead to considerable functional, social, and medical disadvantages.

Can CPVT cause seizures?

The genetic mutations in individuals with CPVT make the RyR2 channel leaky and this is thought to cause the potentially fatal irregular heartbeats. A large proportion of individuals with CPVT also suffer from seizures and these were thought to be caused by changes in the heartbeat.

Can you live a long life with ventricular tachycardia?

Can irregular heartbeat cause seizures?

Both atrial and ventricular arrhythmias can produce transient neurologic symptoms by disrupting cerebral perfusion, but ventricular arrhythmias rarely result in seizures.

What is the pathophysiology of CPVT?

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is characterized by episodic syncope occurring during exercise or acute emotion in individuals without structural cardiac abnormalities. The underlying cause of these episodes is the onset of fast ventricular tachycardia (bidirectional or polymorphic).

How is ventricular tachycardia (CPVT) diagnosed?

Exercise stress test with ECG (the most important test to diagnose CPVT; most people with CPVT have VT when their heart rate is high) Event monitoring may need to wear a portable ECG for about 30 days. Echocardiogram, an ultrasound of the heart to examine blood flow in the heart and check the heart’s function

What is CPTV (CPVT)?

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare condition. It causes an irregular heart rhythm that can be life threatening. It often shows up in childhood, but can show up later in life. The first sign is often fainting or near fainting during exercise or strong emotion.

What are the treatment options for CPVT?

This includes things such as avoiding triggers and taking certain medicines. Your healthcare provider may also recommend an implantable cardioverter defibrillator (ICD). An ICD can detect a problem heart rhythm and give a shock to help stop it. What are the symptoms of CPVT?