Why is direct titration better than back titration?

The main difference between back titration and direct titration is that a back titration determines the concentration of the unknown by determining the remaining amount of the compound with a known concentration whereas a direct titration directly measures the concentration of the unknown compound.

What is difference between direct titration and back titration?

In a direct titration, you add a standard titrant to the analyte until you reach the end point. In a back titration, you add an excess of standard titrant to the analyte, and then you titrate the excess titrant to determine how much is in excess.

How is titration used in medicine?

Titration is a way to limit potential side effects by taking time to see how your body will react to a drug. In titration, the medication is started at a low dose. Every couple of weeks, the dose is raised (“up-titrated”) until the maximum effective dose (“target dose”) has been achieved or side effects occur.

Why did we not titrate the antacid directly?

Stomach antacid tablets are buffered to provide a pH between 3 and 4, the approximate pH of stomach acid. There is no accurate method to titrate the antacids directly. Because of fillers added to the tablets, the antacid tablets, dissolved in the HCl, will not produce a clear solution.

Why back titration is necessary?

A back titration is used when the molar concentration of an excess reactant is known, but the need exists to determine the strength or concentration of an analyte. When direct titration endpoint would be hard to discern (e.g., weak acid and weak base titration) When the reaction occurs very slowly.

What is Karl Fischer principle and reaction?

The principle of Karl Fischer titration is based on the oxidation reaction between iodine and sulphur dioxide. Water reacts with iodine and sulphur dioxide to form sulphur trioxide and hydrogen iodide. An endpoint is reached when all the water is consumed.

What is the importance of titration in pharmacy?

Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. When a drug has a narrow therapeutic index, titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small.

What is the importance of titration to medical technologists medical laboratory scientists?

Titration can be used to determine the concentration of acids, bases, and other substances in blood and urine samples. The titration is usually done automatically by a machine that is interfaced to a computer. It can do either acid-base or reduction-oxidation titrations.