What is Cmia method for HIV?

The ARCHITECT HIV Ag/Ab Combo assay is a chemiluminescent microparticle immunoassay (CMIA) for the simultaneous qualitative detection of human immunodeficiency virus (HIV) p24 antigen and antibodies to HIV type 1 (HIV-1 group M and group O) and/or type 2 (HIV-2) in human serum and plasma (EDTA and heparin).

How does the HIV testing process work?

HIV tests are typically performed on blood or oral fluid. They may also be performed on urine. A NAT looks for the actual virus in the blood and involves drawing blood from a vein. The test can either tell if a person has HIV or tell how much virus is present in the blood (known as an HIV viral load test).

What is HIV combo test?

The most accurate and reliable routinely used diagnostic HIV test is a laboratory test that can detect both HIV antibodies and p24 antigen. They are called combination or combo tests because they detect both substances. They are “fourth-generation” tests, with more advanced technology than the earlier generations.

What generation is Cmia test?

The two current FDA-approved 4th-generation HIV-1/2 combination antigen/antibody chemiluminescent, magnetic microparticle-based immunoassay (CMIA) and enzyme immunoassay (EIA) platform assays have significantly reduced the diagnostic seronegative window period but these assays are still insensitive to the three- to …

What is the difference between RPR and Treponema pallidum?

Syphilis tests are available in two categories: treponemal tests (antibody tests to the organism itself, Treponema pallidum) and non-treponemal tests (such as RPR, which detects non-treponemal reagin antibodies; commonly seen with syphilis, but present in many other disease and non-disease states).

What does a positive RPR blood test mean?

A positive test result may mean that you have syphilis. If the screening test is positive, the next step is to confirm the diagnosis with a more specific test for syphilis, such as FTA-ABS. The FTA-ABS test will help distinguish between syphilis and other infections or conditions.