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Do you lose weight on zonisamide?

Do you lose weight on zonisamide?

Zonisamide is an antiepileptic drug that demonstrated weight loss efficacy in obese adults(−5.9 kg vs −0.9 kg) in a 16-week trial with further weight loss in the additional 16-week extension phase.

Will Sudafed make you lose weight?

Discussion: We conclude that further studies with low-dose PPA for weight loss are indicated, that pseudoephedrine is not effective for weight loss, and that adding benzocaine to phenylpropanolamine increases adverse effects without increasing weight loss.

How much weight can you lose on Zonegran?

Gadde found that Zonegran caused an average weight loss of about 20 pounds in obese people who took it for eight months. The loss approached 10 percent of body weight. By contrast, a placebo group lost only about three pounds. So far, the main side effect of Zonegran has been fatigue.

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What drug can make me lose weight?

Four weight-loss drugs have been approved by the U.S. Food and Drug Administration for long-term use:

  • Bupropion-naltrexone (Contrave)
  • Liraglutide (Saxenda)
  • Orlistat (Xenical)
  • Phentermine-topiramate (Qsymia)

Does zonisamide speed up metabolism?

Zonisamide does not induce its own metabolism. Plasma clearance of zonisamide is approximately 0.30–0.35 mL/min/kg in patients not receiving enzyme-inducing antiepilepsy drugs (AEDs). The clearance of zonisamide is increased to 0.5 mL/min/kg in patients concurrently on enzyme-inducing AEDs.

Will zonisamide make you gain weight?

Longitudinal assessment indicated that zonisamide was associated with a significantly slower rate of BMI and weight increases compared with placebo (P = . 01). No patients in the zonisamide group experienced significant weight gain, compared with 33\% of placebo-treated patients (P = . 009).

Can Sudafed cause weight gain?

If used properly, sinus and allergy medications will not cause weight gain.

Does phenylephrine decrease appetite?

Sleep disturbances, restlessness, rash or itching, loss of appetite, feeling of warmth or redness under the skin.

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How do you take Zonegran for weight loss?

Zonegran is available in 100 mg pills. For the first week, take one pill at bedtime. For the second week, take two pills at bedtime. For the third week, take three pills at bedtime.

Does zonisamide cause loss of appetite?

SIDE EFFECTS: Dizziness, drowsiness, trouble sleeping, lack of coordination, lightheadedness, loss of appetite, diarrhea, and double vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.